cryotherapy heart arrhythmia atrial fibrillation treatment CRYOTHERAPY Safety and practicality are important features associated with cryotherapy in the treatment of cardiac arrhythmias. cryotherapy offers electrophysiologists the ability to test potential ablation sites accurately by inducing a reversible electrical and thermal effect. CryoTherapy procedures also offer increased site precision through CryoAdhesion. It produces well-demarcated cryolesions that heal quickly. Tissue immediately adjacent to a cryolesion demonstrates normal electrical activation. There is also a reduced risk of perforation with cryotherapy. Pre-clinical studies have demonstrated minimal endothelial disruption and thrombus.